It also comes weeks after President Donald Trump's abrupt announcement that he will pull all 2,000 U.S. troops from Syria, which caused alarm among United States allies in the region.
In Jerusalem on Monday, Bolton listed pre-withdrawal "objectives" - including the final defeat of Islamic State and protection of Kurdish allies - that went well beyond Trump's simple assertion that U.S. forces were heading home from Syria.
"By most accounts, Trump´s Middle East policy has made a messy Middle East even messier", said Aaron David Miller on Twitter, a former United States diplomat and now an analyst at Woodrow Wilson Center.
"If we have to, we will strike Syria", Pompeo said.
In his meeting with lower-ranking officials before departing Ankara, Bolton was informed of Turkish demands that the US hand over its Syria bases to the Turkish military or local authorities, disarm the SDF and remove all heavy weapons from eastern Syria, according to Hurriyet and the Turkish Anadolu news agency. He also declared that no foreign aid will be given to Syria until Iranian forces completely withdraw from the country.
"Our leaders gravely misread your history, and ours".
Other extremist factions - such as the Al-Qaeda-linked Hurras Al-Deen group and the Turkestan Islamic Party (TIP) - are present in other areas of Idlib but are allied with HTS, Observatory chief Rami Abdel Rahman said.
But the muddled pronouncements from the Trump administration, which swiftly walked back the planned withdrawal of troops from Syria, has triggered regional concern.
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Cavusoglu told NTV it was not realistic to expect the United States to collect all of the weapons it had supplied to Syrian Kurdish fighters who are viewed by Ankara as terrorists.
The PYD/YPG is the Syrian offshoot of the PKK, a terrorist group recognized by Turkey, the US, and European Union, which in its 30-year terror campaign has taken some 40,000 lives, including women and children.
Identifying as an evangelical Christian, Pompeo lauded the UAE's recognition of Israel at a judo competition late last year, a move he said had been two years in the making.
The fact that Bolton laid the demand for protection of Kurdish fighters as a condition for USA withdrawal from Syria sparked Erdogan's anger.
This comes as National Security Advisor John Bolton, along with officials at the State Department and the Pentagon, has said that there is no timeline because a withdrawal is conditions-based.
"President Trump has reversed our willful blindness to the danger of the regime and withdrew from the failed nuclear deal, with its false promises", Pompeo said.
A Turkish official has said that his country will launch an attack against Kurdish forces in Syria whether or not USA forces pull out first.
"Bolton's remarks in Israel are not acceptable". "Whether or not it withdraws, we will do whatever is necessary against a terrorist organization that threatens our national security".
"It's time for old rivalries to end, for the sake of the greater good of the region", Pompeo said during a Middle East tour to reassure allies about USA plans to withdraw troops from Syria.
Washington has never committed to a date for the announcement of what has been promised to be a possible basis for a final settlement of the Palestinian-Israeli struggle, sometimes dubbed the "deal of the century".
The following day, Mattis resigned, although Trump initially said he was retiring. "But this isn't a change of mission", he said.
In a press statement made in Cairo, Abbas reiterated a statement suggesting that he could not agree to what the Americans seemed to be offering. Others called it a breach of diplomatic norms at the least.