Godolphin has tried for many years to win "The Race That Stops A Nation", and Tuesday at Flemington Racecourse in Australia, the drought ended with a victory by 3-year-old Cross Counter (GB) in the Melbourne Cup for Sheik Mohammed's team, including trainer Charlie Appleby and jockey Kerrin Mcevoy.
Regal Monarch, trained by Chris Waller, was euthanised after falling in race four previous year, while British stayer Red Cadeaux was put down two weeks after falling and breaking a leg in the 2015 Melbourne Cup.
Leading jockey Hugh Bowman has been slapped with a one-month suspension for three separate offences following his Melbourne Cup ride aboard Marmelo.
"Our sympathies are extended to Coolmore and the Williams family, the owners of The Cliffsofmoher, jockey Ryan Moore, trainer Aidan O'Brien and his staff who cared for the horse and are greatly saddened by their loss".
Irish horse The Cliffsofmoher has been euthanased on the Flemington track after sustaining an injury to its shoulder during the Melbourne Cup.
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"This was an unfortunate incident that happens infrequently, with Victoria having one of the best safety records in world racing".
Appleby, who said Godolphin's first Melbourne Cup win would only increase their hunger to win the great race again in future years, paid Kerrin McEvoy an enormous tribute for the win. The Cliffsofmoher suffered a fractured right shoulder when injured in the Melbourne Cup, unfortunately could not be saved.
Channel 7 commentator Bruce McAvaney said it was a "tragedy" while his colleague Richard Freedman had made a point of mentioning how agitated The Cliffsofmoher looked before the race.
Ryan Moore pulls up The Cliffsofmoher after it broke down in the first lap of the Melbourne Cup.
Australians are expected to place more than 35 million individual bets over the four-day Melbourne Cup carnival.
It tarnished a thrilling win by Cross Counter, who saluted ahead of Marmelo and A Prince Of Arran.