That gave the Derby manager the chance to hand debuts to two of his summer signings.
Alongside Aston Villa and Swansea City, Leeds are one of three sides with a 100 percent start and trail only table-topping Middlesbrough - who have played one more game - after they beat Birmingham City 1-0.
Derby improved straight after the break as Harry Wilson fed Mason Mount, but he dragged his shot just wide of the post and just beyond Martyn Waghorn's despairing dive to reach the ball.
Mateusz Klich bent home a stunning strike at the end of a thrilling team move to put the visitors in front inside five minutes at Pride Park on Saturday.More news: Bitcoin & Ripple Technical Analysis - Charts Point to Further Losses
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And while Leeds 'keeper Bailey Peacock-Farrell definitely could have done better, there's no denying the quality of the hit. Tom Lawrence's direct running was too much for Luke Ayling, the right-back bringing down the Welsh global outside the corner of the penalty area. We didn't have control of midfield in the first-half, hence bringing Bradley Johnson on, and although we were initially better we can't just play good games in small bits.
Matheusz Klich opened the scoring for Leeds and despite Tom Lawrence equalising, a Kemar Roofe double and Ezgjan Aliosi's header sent Lampard tumbling to defeat.
Stoke, relegated from the top flight last season, are still searching for their first win after Ollie Watkins cancelled out Benik Afobe's opener in a 1-1 draw against Brentford. Carson was called into action to deny Roofe at point-blank range with Tomori making a last-ditch block to deny Ayling on the rebound. First, Roofe slammed the ball high past Carson to register his second. Pablo Hernandez did brilliantly to reach the ball and pull it back before it went over the by-line and Alioski arrived to power a header into an unguarded net.